Results 91 to 100 of about 606,523 (279)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Spatial structure of contextual modulation
Journal of Vision, 2013 Contextual effects are ubiquitous in vision and provide a means for detectors with localized receptive fields to encode global properties of a stimulus. Although the nature of the neural connections is complex, the majority of evidence supports the Gestalt idea of collinearity; interactions are greatest when the target and surround orientations are ...
I, Mareschal, C W G, Clifford
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Spatial modulation of scalable nanostructures by combining maskless plasmonic lithography and grayscale-patterned strategy. [PDF]
Nanoscale Adv, 2023 Han D, Ye T, Wei Y.
europepmc +1 more source
Bit-interleaved coded spatial modulation
2012 IEEE 23rd International Symposium on Personal, Indoor and Mobile Radio Communications - (PIMRC), 2012 We address coded spatial modulation (CSM) and present a novel approach denoted as bit-interleaved coded spatial modulation (BICSM) with iterative demodulation/decoding. The proposed transceiver architecture alleviates some drawbacks of the previously proposed CSM systems, such as being limited to a particular class of trellis codes or being effective ...
Koca, Mutlu, Sari, Hikmet
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Differential spatial modulation for high-rate transmission systems
EURASIP Journal on Wireless Communications and Networking, 2018 This paper introduces a new differential spatial modulation (DSM) scheme which subsumes both the previously introduced DSM and high-rate spatial modulation (HR-SM) for wireless multiple input multiple output (MIMO) transmission. By combining the codeword
Thu Phuong Nguyen +3 more
doaj +1 more source