Results 91 to 100 of about 3,260,687 (367)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Hyperspectral Features of Oil-Polluted Sea Ice and the Response to the Contamination Area Fraction

Sensors, 2018
Researchers have studied oil spills in open waters using remote sensors, but few have focused on extracting reflectance features of oil pollution on sea ice.
Bingxin Liu, Ying Li, Chengyu Liu, Feng Xie, Jan-Peter Muller   +4 more
doaj   +1 more source

Predicting real world spatial disorientation in Alzheimer’s disease patients using virtual reality navigation tests

Scientific Reports, 2022
Spatial navigation impairments in Alzheimer’s disease (AD) have been suggested to underlie patients experiencing spatial disorientation. Though many studies have highlighted navigation impairments for AD patients in virtual reality (VR) environments, the
Vaisakh Puthusseryppady, Sol Morrissey, Hugo Spiers, Martyn Patel, Michael Hornberger   +4 more
doaj   +1 more source

Quality of self-reported cognition: effects of age and gender on spatial navigation self-reports

Aging & Mental Health, 2020
Subjective measures of cognitive abilities are often used in various environments, such as clinical, experimental, and professional settings. Here, we assess the quality of such measures, specifically looking into the impact of age and gender.
I. V. D. van der Ham, M. V. D. van der Kuil, M. H. Claessen   +2 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Neural correlates of spatial navigation changes in mild cognitive impairment and Alzheimer’s disease

Frontiers in Behavioral Neuroscience, 2014
Although the memory impairment is a hallmark of Alzheimer’s disease (AD), AD has also been characterized by spatial disorientation, which is present from its early stages.
Kamil eVlček, Kamil eVlček, Jan eLaczó, Jan eLaczó   +3 more
doaj   +1 more source

Evaluation of Indoor Paths Based On Indoor Navigation Network Models and Space Syntax Measures

Geodetski Vestnik, 2023
Indoor navigation networks (models) are an essential way to characterize the navigation patterns of pedestrians. To find the most suitable path existing studies concentrate mostly on the minimization of length and turns.
Atakan Bilgili, Alper Sen, Melih Basaraner   +2 more
doaj   +1 more source

Spatial navigation from same and different directions: The role of executive functions, memory and attention in adults with Autism Spectrum Disorder [PDF]

, 2017
To resolve some of the inconsistencies in existing research into spatial navigation in Autism Spectrum Disorder (ASD), we tested two large age- and ability-matched groups of ASD and typically developing (TD) participants for their spatial navigation ...
American Psychiatric Association, American Psychiatric Association, Baron-Cohen, Bennetto, Bigham, Bohbot, Boucher, Boucher, Boucher, Bowler, Bowler, Bowler, Bowler, Bowler, Bowler, Bowler, Burgess, Caron, Condappa, Cooper, Cooper, Dichter, Edgin, Eichenbaum, Eylen, Featherstone, Feigenbaum, Gaigg, Gaigg, Gilotty, Goddard, Goodrich-Hunsaker, Halford, Hamilton, Hannula, Harris, Hartley, Henry, Hill, Hill, Hughes, Jones, Lind, Lind, Lopez, Lord, Loth, Maister, Minshew, Minshew, Minshew, Minshew, Minshew, Minshew, Minshew, Moffat, Moffat, Opitz, Owen, Ozonoff, Panerai, Poirier, Prior, Rehfeldt, Ring, Ring, Ring, Ring, Robinson, Rubin, Rumsey, Rumsey, Smith, Spreng, Tager-Flusberg, The Psychological Corporation, Wiener, Wiener, Williams, Williams, Woodbury-Smith   +80 more
core   +3 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Navigating by Design: Effects of Individual Differences and Navigation Modality on Spatial Memory Acquisition

Behavioral Sciences
Spatial memory is a critical component of spatial cognition, particularly in unfamiliar environments. As navigation systems become integral to daily life, understanding how individuals with varying spatial abilities respond to different navigation modes ...
Xianyun Liu, Yanan Zhang, Baihu Sun
doaj   +1 more source