Results 71 to 80 of about 2,551,132 (297)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Pediatric unilateral spatial neglect: A systematic review

Journal of Pediatric Rehabilitation Medicine, 2021
PURPOSE: Unilateral spatial neglect (USN), an inability to attend to one side of space or one’s body, is commonly reported in adult stroke survivors and is associated with poor outcomes.
Emerson Hart, Emily Grattan, Michelle Woodbury, Teri Lynn Herbert, Patty Coker-Bolt, Heather Bonilha   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A New Standardization of the Bells Test: An Italian Multi-Center Normative Study

Frontiers in Psychology, 2019
Objective: The Bells Test is a cancelation task that is widely used for the diagnosis of unilateral spatial neglect (USN). With the aim of fostering more reliable use of this instrument, we set out to develop new norms adjusted for the possible influence
Mauro Mancuso, Mauro Mancuso, Alessio Damora, Laura Abbruzzese, Eduardo Navarrete, Benedetta Basagni, Giuseppe Galardi, Marina Caputo, Brunella Bartalini, Michelangelo Bartolo, Chiara Zucchella, Maria C. Carboncini, Simona Dei, Pierluigi Zoccolotti, Pierluigi Zoccolotti, Gabriella Antonucci, Gabriella Antonucci, Antonio De Tanti   +17 more
doaj   +1 more source

The prognosis of allocentric and egocentric neglect : evidence from clinical scans [PDF]

, 2012
We contrasted the neuroanatomical substrates of sub-acute and chronic visuospatial deficits associated with different aspects of unilateral neglect using computed tomography scans acquired as part of routine clinical diagnosis.
Chechlacz, Magdalena, Lau Johnny K. L., Pia Rotshtein (122796), Chechlacz, Magdalena; id_orcid, Humphreys, Glyn W., Bickerton, Wai-Ling, Roberts, Katherine L, Chechlacz, M, Rotshtein, P, Wai-Ling Bickerton, Humphreys, Glyn W, Humphreys Glyn W., Baron, Jean-Claude, Pia Rotshtein, Johnny K L Lau, Humphreys, GW, Bickerton Wai-Ling, Roberts, KL, Magdalena Chechlacz (122794), Katherine L. Roberts (122798), Glyn W Humphreys, Lau, Johnny K L, Roberts Katherine L., Rotshtein, Pia, Glyn W. Humphreys (122804), Johnny K. L. Lau (122802), Roberts, Katherine L., Magdalena Chechlacz, Chechlacz Magdalena, Lau, Johnny K. L., Katherine L Roberts, Rotshtein Pia, Wai-Ling Bickerton (122800), Lau, JKL, Bickerton, W-L   +34 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Behavioral and Cortical Effects during Attention Driven Brain-Computer Interface Operations in Spatial Neglect: A Feasibility Case Study

Frontiers in Human Neuroscience, 2017
During the last years, several studies have suggested that Brain-Computer Interface (BCI) can play a critical role in the field of motor rehabilitation.
Luca Tonin, Marco Pitteri, Robert Leeb, Huaijian Zhang, Emanuele Menegatti, Francesco Piccione, Francesco Piccione, José del R. Millán   +7 more
doaj   +1 more source

Hemispatial neglect [PDF]

, 2004
The syndrome of hemispatial neglect is characterised by reduced awareness of stimuli on one side of space, even though there may be no sensory loss. Although it is extremely common, it has proven to be a challenging condition to understand, and to treat.
Husain, M., Parton, A., Malhotra, P.
core  

Eye movements and verbal report in a single case of visual neglect [PDF]

, 2012
In this single case study, visuospatial neglect patient P1 demonstrated a dissociation between an intact ability to make appropriate reflexive eye movements to targets in the neglected field with latencies of
Milner, A David, Benson, Valerie, Ietswaart, Magdalena, Milner, A.D., Magdalena Ietswaart, Magdalena Ietswaart (140209), David Milner (140212), Valerie Benson, David Milner, Milner, David, Letswaart, M., Valerie Benson (140207)   +11 more
core   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source