Results 11 to 20 of about 64,018 (290)
Power analysis for spatial omics [PDF]
, 2022 AbstractAs spatially-resolved multiplex profiling of RNA and proteins becomes more prominent, it is increasingly important to understand the statistical power available to test specific hypotheses when designing and interpreting such experiments. Ideally, it would be possible to create an oracle that predicts sampling requirements for generalized ...
Ethan A. G. Baker +4 more
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SOTIP is a versatile method for microenvironment modeling with spatial omics data
Nature Communications, 2022 Methods that analyse heterogeneity and compare tissue microenvironments using spatial omics data are challenging to develop. Here, the authors present SOTIP, a method that can perform spatial heterogeneity, spatial domain, and differential ...
Zhiyuan Yuan +6 more
doaj +1 more source
Squidpy: a scalable framework for spatial omics analysis [PDF]
Nature Methods, 2022 AbstractSpatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools from omics and image analysis to enable scalable ...
Giovanni Palla +12 more
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DNA‐Barcoded Fluorescence Microscopy for Spatial Omics [PDF]
PROTEOMICS, 2020 AbstractInnovation in genomics, transcriptomics, and proteomics research has created a plethora of state‐of‐the‐art techniques such as nucleic acid sequencing and mass‐spectrometry‐based proteomics with paramount impact in the life sciences. While current approaches yield quantitative abundance analysis of biomolecules on an almost routine basis ...
Schueder, Florian +3 more
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Systems biology in animal sciences [PDF]
, 2011 Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A. +4 more
core +3 more sources
Updates in metabolomics tools and resources: 2014-2015 [PDF]
, 2016 Data processing and interpretation represent the most challenging and time-consuming steps in high-throughput metabolomic experiments, regardless of the analytical platforms (MS or NMR spectroscopy based) used for data acquisition.
Misra, Biswapriya B. +1 more
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Multi-omics analysis in developmental bone biology
Japanese Dental Science Review, 2023 Single-cell omics and multi-omics have revolutionized our understanding of molecular and cellular biological processes at a single-cell level. In bone biology, the combination of single-cell RNA-sequencing analyses and in vivo lineage-tracing approaches ...
Yuki Matsushita +3 more
doaj +1 more source
Situational Awareness Support to Enhance Teamwork in Collaborative Environments [PDF]
, 2008 Modern collaborative environments often provide an overwhelming amount of visual information on multiple displays. The multitude of personal and shared interaction devices leads to lack of awareness of team members on ongoing activities, and awareness of
Dijk, E.M.A.G. van +2 more
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Preclinical Models: Boosting Synergies for Improved Translation [PDF]
, 2020 The field of preclinical models is a very vast arena, in which finding connections among groups acting in apparently very distant research areas can sometimes prove challenging [...
Attanasio C., Sangiovanni M.
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Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. [PDF]
, 2019 MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy.
Agard, Bruno +42 more
core +3 more sources