Results 131 to 140 of about 4,674,553 (309)

A Task-Related EEG Microstate Clustering Algorithm Based on Spatial Patterns, Riemannian Distance, and a Deep Autoencoder

Brain Sciences
Background: The segmentation of electroencephalography (EEG) signals into a limited number of microstates is of significant importance in the field of cognitive neuroscience.
Shihao Pan, Tongyuan Shen, Yongxiang Lian, Li Shi   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Spatiotemporal distribution patterns of cephalopods and their responses to changes in the marine environment in the coastal waters of Zhejiang, China

Frontiers in Marine Science
IntroductionLike pelagic fishes, cephalopods represent fishery resources with high worldwide potential and an important evolutionary node animal group. Thus, exploring the spatial and seasonal variations in cephalopod distribution and their associations ...
Jun Liang, Jun Liang, Yongdong Zhou, Yongdong Zhou, Tian Wu, Feng Chen, Feng Chen, Kaida Xu, Kaida Xu, Guangjie Fang, Yazhou Zhang, Yazhou Zhang   +11 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Research on Evolution of Spatial Pattern of Crude Oil Trade

, 2014
In these years, diversification of import channels has been a important strategy to get the security of petroleum import. However, diversification premises a thorough analysis and understanding of the importing strategy of other countries in advance ...
CHENG, Shujia, LI, Xiumin, SONG, Lanqi
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Disentangling the effect of the spatial scale and species spatial pattern on the abundance–suitability relationship

Knowledge about species abundance across broad spatial areas is crucial for unraveling ecological processes. Yet, abundance estimation often demands extensive sampling effort associated with logistical challenges.
Tarroso, Pedro, Tellería, José L., Acevedo, Pelayo, Fernández-López, Javier, Ferrer-Ferrando, David   +4 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Siaya County Spatial Plan 2018-2028

, 2018
This County Spatial Plan is the first of its kind for Siaya under the new Constitution of Kenya, 2010, which created the 47 county governments Siaya being one of them.

core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source