Results 41 to 50 of about 1,149,841 (288)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transition of mobility in companies – A semi-systematic literature review and bibliographic analysis on corporate mobility and its management

Transportation Research Interdisciplinary Perspectives, 2021
Advancement measures and negative externalities of the current transport system have been extensively researched but significant changes concerning greenhouse gas (GHG) emission reduction is yet to be achieved. The expected mobility changes, triggered by
Tobias Gorges, Christian Holz-Rau
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

An open risk index with learning indicators from OSM-tags, developed by machine learning and trained with the WorldRiskIndex [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
While climate change is already a real issue in many parts of the world, it is even more threatening the well-being of future generations. The SDG 1.5 explicitly aims to reduce the vulnerability and exposure to climate related hazards by 2030.
D. Feldmeyer, H. Sauter, J. Birkmann
doaj   +1 more source

Orchestrating the spatial planning process: from Business Process Management to 2nd generation Planning Support Systems [PDF]

, 2014
Metaplanning can be considered as a necessary step for improving collaboration, transparency and accountability in sustainable and democratic spatial decision-making process.
CAMPAGNA, MICHELE, IVANOV K, MASSA, PIERANGELO   +2 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Between author’s dreams and client’s wishes

Actas de Arquitectura Religiosa Contemporánea
Contemporary praxis of church construction in the Serbian Orthodox Church (SOC) and the client-architect relationship are conditioned by Church tradition and regulations.
Božidar Mani´c , Ana Nikovi´c, Boško Josimovi´c   +2 more
doaj   +1 more source

Relationship between traditional and contemporary elements in the architecture of Orthodox churches at the turn of the millennium [PDF]

Facta Universitatis. Series: Architecture and Civil Engineering, 2015
The paper will present the contemporary practice of church architecture in Bulgarian, Romanian, Russian and Greek orthodox churches, at the end of the XX and the beginning of the XXI century, and analyse the relationship of traditional and ...
Manić Božidar, Niković Ana, Marić Igor   +2 more
doaj   +1 more source

Socio-Spatial Group Queries for Impromptu Activity Planning

, 2015
The development and integration of social networking services and smartphones have made it easy for individuals to organize impromptu social activities anywhere and anytime. Main challenges arising in organizing impromptu activities are mostly due to the
Chen, Ming-Syan, Huang, Liang-Hao, Lee, Wang-Chien, Shen, Chih-Ya, Yang, De-Nian   +4 more
core   +1 more source