Results 41 to 50 of about 38,593 (265)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Collective spatial keyword querying [PDF]

open access: yesProceedings of the 2011 ACM SIGMOD International Conference on Management of data, 2011
With the proliferation of geo-positioning and geo-tagging, spatial web objects that possess both a geographical location and a textual description are gaining in prevalence, and spatial keyword queries that exploit both location and textual description are gaining in prominence.
Xin Cao 0001   +3 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An Efficient Top- $K$ Spatial Keyword Typicality and Semantic Query

open access: yesIEEE Access, 2019
Existing spatial keyword query processing models mainly consider the spatial proximity and text relevancy between spatial objects and spatial keyword query, which usually makes the top-k answer objects are similar to each other.
Xiaoyan Zhang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

GSA: node failures tolerent spatial window query processing algorithm in wireless sensor networks

open access: yesTongxin xuebao, 2008
A node failures tolerent spatial window query processing algorithm called GSA was proposed. The grid size parameter was studied and a grid-based data collection schedule scheme to avoid the message collisions in the process of data collection was ...
LIU Liang   +3 more
doaj  

Top-k sentiment analysis over spatio-temporal data [PDF]

open access: yesPeerJ Computer Science
In recent years, social media has become much more popular to use to express people’s feelings in different forms. Social media such as X (i.e., Twitter) provides a huge amount of data to be analyzed by using sentiment analysis tools to examine the ...
Abdulaziz Almaslukh   +5 more
doaj   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

ANALISA KECEPATAN SPATIAL QUERY DATA SATELIT PADA BEBERAPA STORAGE ENGINE MYSQL DATABASE

open access: yesMatrix: Jurnal Manajemen Teknologi dan Informatika, 2016
Penerapan spatial database untuk data satellite remote sensing, membutuhkan struktur data yang memungkinkan proses spatial query dilakukan dengan kecepatan tinggi, oleh karena volume data satelit biasanya sangat besar.
I Ketut Swardika
doaj  

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