Results 81 to 90 of about 22,408 (308)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Location-Based Aggregate Queries for Heterogeneous Neighboring Objects

open access: yesIEEE Access, 2017
Currently, most of the processing techniques for the conventional location-based queries focus only on a single type of objects. However, in real-life applications, the user may be interested in obtaining information about different types of objects, in ...
Yuan-Ko Huang
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Energy-efficient and privacy-preserving spatial range aggregation query processing in wireless sensor networks

open access: yesInternational Journal of Distributed Sensor Networks, 2019
The existing privacy-preserving aggregation query processing methods in sensor networks rely on pre-established network topology and require all nodes in the network to participate in query processing.
Liang Liu, Zhenhai Hu, Lisong Wang
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Processing of Spatial-Keyword Range Queries in Apache Spark [PDF]

open access: gold, 2023
Aggelos Karabinos   +3 more
openalex   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

AHS Model: Efficient Topological Operators for a Sensor Web Publish/Subscribe System

open access: yesISPRS International Journal of Geo-Information, 2017
The Worldwide Sensor Web has been applied for monitoring the physical world with spatial and temporal scales that were impossible in the past. With the development of sensor technologies and interoperable open standards, sensor webs generate tremendous ...
Chih-Yuan Huang, Steve H. L. Liang
doaj   +1 more source

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