Results 61 to 70 of about 607,674 (294)
Catadioptric hyperspectral imaging, an unmixing approach
Hyperspectral imaging systems provide dense spectral information on the scene under investigation by collecting data from a high number of contiguous bands of the electromagnetic spectrum. The low spatial resolutions of these sensors frequently give rise
Didem Ozisik Baskurt +2 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Adaptive Gap-Filling of Multispectral Images at Coarse and Fine Spatial Resolution
Optical fine and coarse spatial resolution multispectral images are essential for monitoring land surface processes but are often affected by gaps due to cloud contamination and other factors.
Seyedkarim Afsharipour +3 more
doaj +1 more source
Understorey vegetation plays an important role in many ecosystems, yet identifying and monitoring understorey vegetation through remote sensing has proved a challenge for researchers and land managers because understorey plants tend to be small ...
Lorna Hernandez-Santin +3 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The new generation sensor VIIRS of Suomi NPP satellite has replaced MODIS sensors of TERRA & AQUA. VIIRS spectral channels are not full analogues of MODIS, and their spatial resolution differs slightly.
D. V. Pchel’nikov, N. N. Dobtretsov
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

