Results 41 to 50 of about 674,103 (264)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

PENGUKURAN KUALITAS CITRA DIGITAL COMPUTED RADIOGRAPHY MENGGUNAKAN PROGRAM PENGOLAH CITRA

Jurnal Pendidikan Fisika Indonesia, 2016
Penelitian yang telah dilakukan adalah pembuatan dan penghitungan kualitas citra digital menggunakan program Modulation Transfer Function (MTF) pada sistem Computed Radiography (CR) untuk kegiatan Quality Control (QC).
D. R. Ningtias, S. Suryono, S. Susilo
doaj   +1 more source

Spatial Resolution Enhancement of Brillouin Optical Correlation-Domain Reflectometry Using Convolutional Neural Network: Proof of Concept

IEEE Access, 2021
Brillouin optical correlation-domain reflectometry (BOCDR) is a fiber-optic distributed sensing technique with single-end accessibility and high spatial resolution. In BOCDR, the measured Brillouin gain spectrum (BGS) distribution is generally given by a
Jelah N. Caceres, Kohei Noda, Guangtao Zhu, Heeyoung Lee, Kentaro Nakamura, Yosuke Mizuno   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Deep Learning Approach to Improve Spatial Resolution of GOES-17 Wildfire Boundaries Using VIIRS Satellite Data

Remote Sensing
The rising severity and frequency of wildfires in recent years in the United States have raised numerous concerns regarding the improvement in wildfire emergency response management and decision-making systems, which require operational high temporal and
Mukul Badhan, Kasra Shamsaei, Hamed Ebrahimian, George Bebis, Neil P. Lareau, Eric Rowell   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Application of Iolite in Data Reduction of Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry Line-scan Analysis

Yankuang ceshi, 2017
Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) serves as an important tool for assessing variations in elemental/isotopic compositions of rocks and minerals.
ZHU Bi, ZHU Zhi-yong, LÜ Miao, YANG Tao
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source