Results 31 to 40 of about 674,103 (264)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Seq-Scope-eXpanded: spatial omics beyond optical resolution
Nature CommunicationsSequencing-based spatial transcriptomics (sST) enables transcriptome-wide gene expression mapping but falls short of reaching the optical resolution (200–300 nm) of imaging-based methods.
Angelo Anacleto +23 more
doaj +1 more source
Applied Sciences, 2018 The influence of driving conditions on the phase-modulation ability of an optically addressable spatial-light modulator (OASLM) is investigated using an equivalent circuit method and a system for measuring wave-front modulation that uses a phase ...
Lili Pei +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Spatial Resolution of Attenuation Imaging
Archives of Acoustics, 2014 The attenuating properties of biological tissue are of great importance in ultrasonic examination even though its anatomical variability limits diagnostics effectiveness.
Ziemowit KLIMONDA +2 more
doaj
The Spatial Resolution of Visual Attention
Cognitive Psychology, 2001 Two tasks were used to evaluate the grain of visual attention, the minimum spacing at which attention can select individual items. First, observers performed a tracking task at many viewing distances. When the display subtended less than 1 degrees in size, tracking was no longer possible even though observers could resolve the items and their motions ...
J, Intriligator, P, Cavanagh
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Robust Beamforming Based on Weighted Vector Norm Regularization
IEEE Access, 2021 Steering vector mismatch rapidly degrades the performance of the minimum variance distortionless response beamformer. To solve this problem, a robust beamforming method based on weighted vector norm regularization is proposed.
Xiaoying Ren +3 more
doaj +1 more source