Results 21 to 30 of about 2,123,428 (248)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Multi-resolution Tensor Learning for Large-Scale Spatial Data [PDF]
High-dimensional tensor models are notoriously computationally expensive to train. We present a meta-learning algorithm, MMT, that can significantly speed up the process for spatial tensor models.
Yu, Rose, Yue, Yisong, Zheng, Stephan
core +1 more source
Multifunctional in vivo vascular imaging using near-infrared II fluorescence
In vivo real-time epifluorescence imaging of mouse hindlimb vasculatures in the second near-infrared region (NIR-II, 1.1~1.4 microns) is performed using single-walled carbon nanotubes (SWNTs) as fluorophores.
Cooke, John P. +7 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
In this paper, we address the issue of hyperspectral pan-sharpening, which consists in fusing a (low spatial resolution) hyperspectral image HX and a (high spatial resolution) panchromatic image P to obtain a high spatial resolution hyperspectral image ...
de Vieilleville, François +3 more
core +1 more source
Applied Fiber Optic Measurement for Geohydraulic Engineering [PDF]
Engineers have long sought the possibility of measuring parameters such as temperature and pressure continuously in the underground with high precision, high spatial resolution and high band width of parameters. Distributed fibre optic measurement offers
Nishigaki, Makoto, Schreck, Martin
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Lateral and axial resolution criteria in incoherent and coherent optics and holography, near- and far-field regimes [PDF]
This work presents an overview of the spatial resolution criteria in classical optics, digital optics and holography. Although the classical Abbe and Rayleigh resolution criteria have been thoroughly discussed in the literature, there are still several ...
Latychevskaia, Tatiana
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source

