Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Correction: Detection of differentially expressed genes in spatial transcriptomics data by spatial analysis of spatial transcriptomics: A novel method based on spatial statistics. [PDF]
Qiu Z +5 more
europepmc +1 more source
Discussion on Competition for Spatial Statistics for Large Datasets. [PDF]
Flury R, Furrer R.
europepmc +1 more source
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
Mapping intracellular dynamics across the whole cell with spatial statistics. [PDF]
Okabe Y +4 more
europepmc +1 more source
Gray matter microstructure differences in autistic males: A gray matter based spatial statistics study. [PDF]
DiPiero MA +5 more
europepmc +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
Practical AI-based cell extraction and spatial statistics for large 3D bone marrow tissue images. [PDF]
Adams G +6 more
europepmc +1 more source
Sex differences, asymmetry, and age-related white matter development in infants and 5-year-olds as assessed with tract-based spatial statistics. [PDF]
Kumpulainen V +13 more
europepmc +1 more source
Convergence in Mississippi: A Spatial Approach. [PDF]
Mississippi constitutes an interesting case study for analyzing the income convergence process because of several characteristics, such as the fairly large number of counties, its relative homogeneous economy and its low percapita income compared with ...
Mihai Nica
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