Results 61 to 70 of about 323,364 (251)

A Spatial Analysis of the Relationship between Vegetation and Poverty

open access: yesISPRS International Journal of Geo-Information, 2018
The goal of this paper was to investigate poverty and inequities that are associated with vegetation. First, we performed a pixel-level linear regression on time-series and Normalized Difference Vegetation Index (NDVI) for 72 United States (U.S.) cities ...
Teddy Dawson   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Quantifying the spatial heterogeneity of geographical flows

open access: yesGeo-spatial Information Science
Geographical flows describe the movements and connections of materials, energy, and information among locations and are commonly represented by origin-destination (OD) flows (flows for short).
Hua Shu   +8 more
doaj   +1 more source

DOES GEOGRAPHICAL LOCATION MATTER? ASSESSING SPATIAL PATTERNS IN PERCEIVED QUALITY OF LIFE IN EUROPEAN CITIES

open access: yesEuropean Journal of Geography, 2023
The Quality of Urban Life is one of the most important issues of the present policies, being highly researched. The spatial dimension of this concept is still a major challenge for both researchers and policy makers as it was not enough explored and ...
Lucian ROȘU   +2 more
doaj  

NEW MEAN VALUES FOR HOMOGENEOUS SPATIAL TESSELLATIONS THAT ARE STABLE UNDER ITERATION

open access: yesImage Analysis and Stereology, 2010
Homogeneous random tessellations in the 3-dimensional Euclidean space are considered that are stable under iteration – STIT tessellations. A classification of vertices, segments and flats is introduced and a couple of new metric and topological mean ...
Christoph Thäle, Viola Weiss
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Highest Gradient Model: A New Method for Analytical Assessment of the Efficiency of LiDAR-Derived Visualization Techniques for Landform Detection and Mapping

open access: yesRemote Sensing, 2017
ALS-derived raster visualization techniques have become common in recent years, opening up new possibilities for subtle landform detection in earth sciences and archaeology, but they have also introduced confusion for users.
Alfredo Mayoral   +4 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Optimal orientations of discrete global grids and the Poles of Inaccessibility

open access: yesInternational Journal of Digital Earth, 2020
Spatial analyses involving binning often require that every bin have the same area, but this is impossible using a rectangular grid laid over the Earth or over any projection of the Earth.
Richard Barnes
doaj   +1 more source

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