Results 51 to 60 of about 4,261,904 (264)

Using INLA to fit a complex point process model with temporally varying effects – a case study [PDF]

open access: yes, 2012
Integrated nested Laplace approximation (INLA) provides a fast and yet quite exact approach to fitting complex latent Gaussian models which comprise many statistical models in a Bayesian context, including log Gaussian Cox processes. This paper discusses
Soerbye, S   +7 more
core  

MEAN VALUES FOR HOMOGENEOUS STIT TESSELLATIONS IN 3D

open access: yesImage Analysis and Stereology, 2011
Recently (Nagel and Weiss, 2005), the class of homogeneous random tessellations that are stable under the operation of iteration (STIT) was introduced. In the present paper this model is reviewed and new results for the mean values of essential geometric
Werner Nagel, Viola Weiss
doaj   +1 more source

Comparing Bayesian Spatial Conditional Overdispersion and the Besag–York–Mollié Models: Application to Infant Mortality Rates

open access: yesMathematics, 2021
In this paper, we review overdispersed Bayesian generalized spatial conditional count data models. Their usefulness is illustrated with their application to infant mortality rates from Colombian regions and by comparing them with the widely used Besag ...
Mabel Morales-Otero   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Social Networks and Social Cohesion in the Netherlands: Insights from Combined Administrative and Survey Data

open access: yesSocial Sciences
Statistics Netherlands (CBS) has recently developed the whole population network (Person Network) file, based on administrative microdata, which includes over a billion interpersonal relationships among approximately 17 million inhabitants of the ...
Dino Pitoski, Hans Schmeets
doaj   +1 more source

MGWR: A Python Implementation of Multiscale Geographically Weighted Regression for Investigating Process Spatial Heterogeneity and Scale

open access: yesISPRS International Journal of Geo-Information, 2019
Geographically weighted regression (GWR) is a spatial statistical technique that recognizes that traditional ‘global’ regression models may be limited when spatial processes vary with spatial context.
Taylor M. Oshan   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Spatial Wavelet Statistics of SAR Backscatter for Characterizing Degraded Forest: A Case Study From Cameroon

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2015
Forest degradation is an important issue in global environmental studies, albeit not yet well defined in quantitative terms. The present work addresses the problem, by starting with the assumption that forest spatial structure can provide an indication ...
Elsa C. De Grandi   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Analysis of Vital Statistics [PDF]

open access: yes, 2021
OCLC ...
Grenada. Central Statistics Office.
core  

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