Results 61 to 70 of about 387,386 (299)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2015 Forest degradation is an important issue in global environmental studies, albeit not yet well defined in quantitative terms. The present work addresses the problem, by starting with the assumption that forest spatial structure can provide an indication ...
Elsa C. De Grandi +3 more
doaj +1 more source
Competition on Spatial Statistics for Large Datasets
, 2021 As spatial datasets are becoming increasingly large and unwieldy, exact inference on spatial models becomes computationally prohibitive. Various approximation methods have been proposed to reduce the computational burden.
Sun, Ying +5 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Moving motivated by work or proximity to family and labour market outcomes in the Netherlands
GenusThe classical human-capital model of migration posits that internal migration should lead to improved individual labour market outcomes. However, later empirical and theoretical work has emphasised that the outcomes of migration may be positive for some,
Clara H. Mulder, Niels Kooiman
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Asian Architecture and Building Engineering, 2017 In this study we examined the relationships between the built environment and urban air temperature in Seoul city, Korea. We developed multivariate regression models that address the relationship between built environment characteristics and the ambient ...
Sugie Lee, Jaehyun Ha, Hyemin Cho
doaj +1 more source
Summary statistics for spatio-temporal point processes on linear networks
We propose novel second/higher-order summary statistics for inhomogeneous spatio-temporal point processes when the spatial locations are limited to a linear network.
Moradi, Mehdi +3 more
core +1 more source
p-value approximations for spatial scan statistics using extreme value distributions
, 2015 Spatial scan statistics are widely applied to identify spatial clusters in geographic disease surveillance. To evaluate the statistical significance of detected clusters, Monte Carlo hypothesis testing is often used because the null distribution of ...
정인경
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source