Results 91 to 100 of about 19,178,163 (215)
Advanced Science, EarlyView.A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li +9 more
wiley +1 more source
Advanced Science, EarlyView.An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu +7 more
wiley +1 more source
Tunable Chemical and Optical Modulation of ER-Plasma Membrane Contact-Site Geometry, Dynamics, and Protein Recruitment with High-Fidelity Visualization. [PDF]
Anal ChemZhang S, Fei J, Zheng Y, Zhou R.
europepmc +1 more source
Advanced Science, EarlyView.Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
From one tree to the canopy: an evolutionary design trajectory for tethered robotics in forest environments. [PDF]
Front Robot AIRomanello L, Kocer BB, Kovac M.
europepmc +1 more source
A Thickness‐Invariant Origami Robot With Integrated Actuation and Multimodal Locomotion
Advanced Science, EarlyView.A thickness‐invariant variation on the Yoshimura origami pattern is used as the basis of a robot, allowing power, actuation, and control systems to be embedded within the thickened panels of the pattern. The robot uses multiple kinematic branches to achieve distinct modes of locomotion, such as walking, running, galloping, and turning. ABSTRACT Origami
Davis Wing +4 more
wiley +1 more source
On Determination of Force on Bead-Surface Linker Proteins-Comment on a Recent Paper on Small. [PDF]
SmallDezhkam R, Zhu C.
europepmc +1 more source
Advanced Science, EarlyView.A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith +11 more
wiley +1 more source
Tethered UAV Autonomous Knotting on Environmental Structures for Transport. [PDF]
Cyborg Bionic SystJin R, Xu X, Yang Y, Li J, Cao M, Xie L.
europepmc +1 more source
Wave-absorbing control of transverse vibration of tether system
, 2003 Wave absorbing control is studied for application to vibration suppression on transverse vibration of flexible tethers of space tether systems. The flexibility of the tether is taken into consideration for the analysis and the transverse motion is ...
Hironori Fujii (17359989) +2 more
core