Results 81 to 90 of about 586,818 (301)

Applications of Location-Based Services and Mobile Technologies in K-12 Classrooms

ISPRS International Journal of Geo-Information, 2017
The use of location-based services and mobile technologies is increasing in K-12 classrooms. In this article, we describe the history and the current use of these tools in the innovative Geospatial Semester project in Virginia.
Robert Kolvoord, Kathryn Keranen, Paul Rittenhouse   +2 more
doaj   +1 more source

Influence of Social Multiliteracy Models on Student's Spatial Thinking Skill on Social Studies [PDF]

, 2017
This research is motivated the low of student's spatial thinking skill in solving social problems related to the spatial context, This problem will greatly affect the life of the society such as observations made by BNPB about the flood disaster in ...
Muraida, N. L. (Nurul), Sundari, N. (Nina)   +1 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cognitive performance in multiple system atrophy [PDF]

, 1992
The cognitive performance of a group of patients with multiple system atrophy (MSA) of striato-nigral predominance was compared with that of age and IQ matched control subjects, using three tests sensitive to frontal lobe dysfunction and a battery ...
James, M., Lange, Klaus W., Marsden, C. D., Owen, A. M., Quinn, N. P., Robbins, T. W.   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Effect of Creating 3D Objects with Block Codes on Spatial and Computational Thinking Skills

Informatics in Education
This study investigated the effects of 3D model building activities with block codes on students' spatial thinking and computational thinking skills. The study group consists of 5th grade students in a secondary school in the Central Anatolia region of ...
Mehmet Küçük, Tarık Talan, Muhammet Demirbilek   +2 more
doaj   +1 more source

Penerapan Media Pembelajaran Spasial Pada Mata Pelajaran Geografi Untuk Meningkatkan Kemampuan Berpikir Spasial Peserta Didik SMA Muhammadiyah 7 Panceng Kabupaten Gresik [PDF]

, 2018
This research aims to (1) know the application of spatial learning media on geography subjects in SMA Muhammadiyah 7 Panceng Gresik (2) know the learning result of geography using spatial learning media, and (3) know the improvement of spatial thinking ...
, Siti Azizah Susilawati, S.Si, MP., Khosi'ah, Munisya'ul   +1 more
core  

Spatial thinking and policymaking in the UK: a spatial planning perspective

Space and Polity, 2022
There has been a lack of coherent spatial thinking in policymaking in the UK due to political and economic considerations. This discussion, based on a spatial planning perspective, explains how the UK government’s often aspatial approach to policymaking and hiding behind the façade of market-led ideology does not stand the test when examining the R&
openaire   +2 more sources