Results 101 to 110 of about 9,112 (298)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Media Conglomeration and Worker Commodification: Analyzing the Political Economy of Media Spatialization in Indonesia [PDF]

open access: yes
The rapid transformation of the media industry, marked by conglomeration and spatialization, raises concerns about the commodification of media workers.
Sunandar, Asep, Briandana, Rizki
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Le sujet en langue des signes française

open access: yesTIPA. Travaux interdisciplinaires sur la parole et le langage, 2018
Impersonal constructions are a highly debated issue in the studies of spoken languages, especially regarding the description of the Romance and Slavic languages. Impersonal constructions are linguistically distinguished from personal constructions, i. e.
Myriam Charpentier
doaj   +1 more source

The Impact of Spatial Scales and Spatial Smoothing on the Outcome of Bayesian Spatial Model

open access: yesPLoS ONE, 2013
Discretization of a geographical region is quite common in spatial analysis. There have been few studies into the impact of different geographical scales on the outcome of spatial models for different spatial patterns. This study aims to investigate the impact of spatial scales and spatial smoothing on the outcomes of modelling spatial point-based data.
Kang, Su   +2 more
openaire   +5 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The Empire of the Dead and the Empire of the Living: John Fiske and the Spatialization of Tradition [PDF]

open access: yes, 1997
The Empire of the Dead and the Empire of the Living: John Fiske and the Spatialization of ...
Clark, Michael D.
core   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Embodied Origins of the Spatialization of Abstract Concepts

open access: yes, 2018
Data from: "Embodied origins of the spatialization of abstract concepts: Cross-linguistic evidence from sign languages." Manuscript under ...
Kevin J. Holmes
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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