Results 51 to 60 of about 9,112 (298)

Spatial Coupling of Population and Economic Densities and the Effect of Topography in Anhui Province, China, at a Grid Scale

open access: yesLand, 2023
The spatial coupling of population and economy is an important indicator that reflects regional differences and measures the coordination degree of industrial layouts and environments.
Zhen Yang   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Sound Spatialization Framework: An Audio Toolkit for Virtual Environments

open access: yes, 1998
The Sound Spatialization Framework is a C++ toolkit and development environment for providing advanced sound spatialization for virtual reality and multimedia applications.
Herder, Jens
core   +1 more source

Real-Time 3D Audio Spatialization Tools for Interactive Performance

open access: yes, 2014
Spatial position is one of the main perceivable sound characteristics. Due to historical and technological reasons, however, it has been not fully exploited until last decades.
Pérez-López, Andrés
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Topographies of Hate: Islamophobia in Cyberia [PDF]

open access: yesCyberspace Studies, 2018
Islamophobia’s occurrence in any particular country has little do with the presence of Muslim; it is possible to be Islamophobic when there are virtually no Muslim around.
Salman Sayyid
doaj   +1 more source

Measuring the spatial accuracy of the spatial scan statistic [PDF]

open access: yesSpatial and Spatio-temporal Epidemiology, 2011
The spatial scan statistic is well established in spatial epidemiology. However, studies of its spatial accuracy are infrequent and vary in approach, often using multiple measures which complicate the objective ranking of different implementations of the statistic. We address this with three novel contributions.
Read, S.   +3 more
openaire   +6 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Drivers of change: how the food system of the Lisbon Metropolitan Area is being shaped by activities, initiatives and citizens needs towards a sustainable transition

open access: yesCidades, Comunidades e Território, 2021
Food has always been an urban issue. The role of cities in building more sustainable food systems is already recognized and related to other urban domains, such as transport, health, land use planning for agriculture and multifunctional areas, community ...
Teresa Marat-Mendes   +6 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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