Results 71 to 80 of about 9,112 (298)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Comment étudier la complexité des séries télévisées ? : vers une approche spatiale

open access: yesTV Series, 2019
How to study the specificity of television series building evolving, shapeshifting, open, fragmented narratives? Questioning the use of the notion of complexity within and beyond narratology, this article proposes to read television series through an ...
Mireille Berton, Marta Boni
doaj   +1 more source

Spatial attention and the apprehension of spatial relations. [PDF]

open access: yesJournal of Experimental Psychology: Human Perception and Performance, 1994
Seven experiments examined the role of spatial attention in apprehending spatial relations above, below, left, and right. In Experiment 1, visual search was difficult when targets differed from distractors only in the spatial relation between their elements. Reaction time increased linearly with display size with a slope greater than 60 ms/item.
openaire   +4 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Physical Gesture, Spatialization, Form and Transformation in Watershed I/IV, for Solo Percussion and Real-time Computer Spatialization, by Roger Reynolds [PDF]

open access: yes, 2009
Watershed I/IV, for Solo Percussion and Real-time Computer Spatialization was composed in 1995 by Pulitzer prize-winning composer Roger Reynolds. This work is a 25-minute choreographed music drama for one multiple-percussionist, in which Reynolds ...
Licata, Julie M.
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Analysis of Machine Learning Performance in Spatial Interpolation of Rainfall Data

open access: yesIEEE Access
The spatialization of precipitation data is crucial for studies on climatology, agriculture, and climate change, as well as for urban and environmental planning. Established spatial interpolation methods such as Inverse Distance Weighting are widely used
Alexandre E. L. Nobrega   +1 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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