Results 71 to 80 of about 7,519 (215)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Non-Hermitian gauged topological laser arrays

, 2018
Stable and phase-locked emission in an extended topological supermode of coupled laser arrays, based on concepts of non-Hermitian and topological photonics, is theoretically suggested.
Longhi, Stefano
core   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Extreme Nonlinear Optics in a Femtosecond Enhancement Cavity

, 2011
Intrinsic to the process of high-order harmonic generation is the creation of plasma and the resulting spatiotemporal distortions of the driving laser pulse.
A. Cingöz, A. E. Siemgman, D. C. Yost, J. Ye, T. K. Allison   +4 more
core   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Parametric Forcing of Waves with Non-Monotonic Dispersion Relation: Domain Structures in Ferrofluids?

, 1996
Surface waves on ferrofluids exposed to a dc-magnetic field exhibit a non-monotonic dispersion relation. The effect of a parametric driving on such waves is studied within suitable coupled Ginzburg-Landau equations.
A. Elhefnawy, B. Malomed, D. Raitt, D. Raitt, D. Walgraef, David Raitt, E. Bodenschatz, F. Busse, G. de Surgy, G. Taylor, H. Brand, H. Brand, H. Brand, H. Riecke, H. Riecke, H. Riecke, H. Riecke, Hermann Riecke, I. Rehberg, J. He, J. Hegseth, J. Stuart, L. Kramer, M. Cross, M. de la Torre-Juarez, M. Proctor, P. Coullet, P. Coullet, R. Deissler, R. Rosensweig, R. Rosensweig, R. Tagg, S. Residori, T. Benjamin, W. Eckhaus, W. Pesch, Y. Pomeau   +36 more
core   +1 more source

Electric‐Field Control of Terahertz Response via Spin‐Corner‐Layer Coupling in Altermagnetic Bilayers

Advanced Science, EarlyView.
A spin‐corner‐layer coupling mechanism is proposed in 2D altermagnetic bilayers. Exemplified by NiZrI6, the spin, layer, and topological corner states are simultaneously controlled by an ultralow electric field, enabling active modulation of terahertz absorption, emission, and polarization.
Jianhua Wang, Yilin Han, Shifeng Qian, Zhenxiang Cheng, Wenhong Wang, Zhi‐Ming Yu, Xiaotian Wang   +6 more
wiley   +1 more source

Reversible and Controllable Transition Between Filamentary and Interfacial Resistive Switching in HfO2‐Based Memristors

Advanced Electronic Materials, EarlyView.
5 nm HfO2 memristors exhibit a fully reversible, voltage‐controlled transition between filamentary and interfacial switching within the same device. At high voltages, a filament forms and dominates the conduction, whereas at lower voltages the device reversibly returns to interfacial mode without defect accumulation, implying a new reversible ...
Cuo Wu, Hao Shen, Richard Schroedter, Chong Peng, Hampus Hoffman, Stefan Slesazeck, Ronald Tetzlaff, Thomas Mikolajick, Benjamin Max   +8 more
wiley   +1 more source

A Review of Trans‐Dimensional Kirigami: From Compliant Mechanism to Multifunctional Robot

Advanced Intelligent Systems, EarlyView.
This review outlines recent advancements in the geometric design and mechanical properties of kirigami. The kirigami is classified into two categories from a compliant mechanism perspective, highlighting their applications in metamaterials and robotic systems. Finally, the future research directions, is explored focusing on the potential of integrating
Yang Yu, Jinyao Zhang, Dengchen Wang, Yanqi Yin, Yehui Wu, Ruiyu Bai, Jiaqiang Yao, Yupei Zhang, Jingwen Yin, Chao Tang, Alexey S. Fomin, Wenjie Sun, Chen Liu, Bo Li, Guimin Chen   +14 more
wiley   +1 more source