Results 61 to 70 of about 50,597 (276)

The Impact of Leadership Styles on Employees’ Psychological Empowerment, in Greek Sport Departments [PDF]

Sport Mont, 2019
Effective leadership is a matter of constant concern as a sequence of factors hampers employees’ capabilities and their progress, team spirit, the establishment of collaboration, a common vision for the future, policymaking and finally, the configuration
Lefkothea Tsevaridou, Ourania Matsouka
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A comprehensive and detailed within-host modeling study involving crucial biomarkers and optimal drug regimen for type I Lepra reaction: A deterministic approach

Computational and Mathematical Biophysics, 2023
Leprosy (Hansen’s disease) is an infectious, neglected tropical disease caused by the Mycobacterium Leprae (M. Leprae). About 2,02,189 new cases are diagnosed worldwide each year.
Nayak Dinesh, Chhetri Bishal, Vamsi Dasu Krishna Kiran, Muthusamy Swapna, Bhagat Vijay M.   +4 more
doaj   +1 more source

Regional Characteristics of Precipitation in the Nanpan River Basin, China

Frontiers in Environmental Science, 2022
Nanpan River is the source of the Pearl River in China, and thus, the exploitation of water resources in the Nanpan River Basin directly affects development in its middle and lower reaches. In the present study, the availability of water resources in the
Xinlong Qin, Long Wang, Xuehui Li, Hang Yu, Kui Wang, Defang Fan   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Combined Prediction Model of Gas Concentration Based on Indicators Dynamic Optimization and Bi-LSTMs

Sensors, 2023
In order to accurately predict the gas concentration, find out the gas abnormal emission in advance, and take effective measures to reduce the gas concentration in time, this paper analyzes multivariate monitoring data and proposes a new dynamic combined
Yujie Peng, Dazhao Song, Liming Qiu, Honglei Wang, Xueqiu He, Qiang Liu   +5 more
doaj   +1 more source

Population genetic dynamics in the French Guiana region [PDF]

, 2008
International audienceThree sets of genetic markers (blood group plus protein polymorphisms, mitochondrial DNA and Y-chromosome) were compared in four French Guiana and one Brazilian Amerindian populations. Spearman's rank correlation coefficient between
Callegari-Jacques, Sidia Maria, Crubézy, Eric, Dugoujon, Jean-Michel, Larrouy, Georges, Mazières, Stéphane, Salzano, Francisco Mauro, Sevin, André   +6 more
core   +2 more sources

Reliability and clinical usefulness of the personality inventory for DSM-5 in clinically referred adolescents. A preliminary report in a sample of Italian inpatients [PDF]

, 2016
Background The DSM-5 Alternative Model of Personality Disorders (AMPD) provides the opportunity to integrate the needed developmental perspective in the assessment of personality pathology. Based on this model, Krueger and colleagues (2012) developed the
Ardizzone, I, Borroni, S, Fantini, Fiorella, Ferrara, Mauro, Fossati, A, Krueger, Rf, Markon, Ke, Somma, A, Terrinoni, Arianna, Williams, Riccardo   +9 more
core   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source