Results 101 to 110 of about 11,672,769 (309)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Special Libraries, January 1966 [PDF]
Volume 57, Issue 1https://scholarworks.sjsu.edu/sla_sl_1966/1000/thumbnail ...
Special Libraries Association
core +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Special Libraries, September 1941 [PDF]
Volume 32, Issue 7https://scholarworks.sjsu.edu/sla_sl_1941/1006/thumbnail ...
Special Libraries Association
core +6 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Special Libraries, January-February 1919 [PDF]
Volume 10, Issue 1https://scholarworks.sjsu.edu/sla_sl_1919/1000/thumbnail ...
Special Libraries Association
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Contributor biographies for special issue Thinking with ...
Special issue Thinking with Glissant
doaj +1 more source
Special Libraries, November 1953 [PDF]
Volume 44, Issue 9https://scholarworks.sjsu.edu/sla_sl_1953/1008/thumbnail ...
Special Libraries Association
core +2 more sources

