Results 31 to 40 of about 381,958 (265)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

EDUCATIONAL DEVELOPMENT PRIORITIES FOR PEOPLE WITH SPECIAL NEEDS IN UKRAINE

open access: yesEducation: Modern Discourses, 2018
The article is an attempt to outline general aspects of educational system reforming for the people with special needs in Ukraine, to disclose concisely the key ways of modernization, and to characterize positive shifts in educational area.
Viacheslav Zasenko, Lesya Prokhorenko
doaj   +1 more source

Special Aspects of Using Modern Multimedia Technologies within the Educational Process

open access: yesInternational Journal of Information and Education Technology, 2022
The use of modern multimedia technologies during the educational process is becoming more and more specific due to the multimedia penetration into different learning processes. This article aims to identify the special aspects of using multimedia technologies within the educational process in a distance learning environment. The research methodology is
Oleksandr Priadko   +5 more
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Geistig behinderte Kinder religiös erziehen – Herausforderungen an Pädagogik und Katechese

open access: yesThe Person and the Challenges, 2014
Special education options are diverse and prepared to meet the needs of children with varying degrees of intellectual disabilities. However, many parents of children with an intellectual disability have a difficult time in organizing the ...
Józef Stala
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

What’s Not Being Discussed, or Considered, in Science Publishing?

open access: yesJournal of Microbiology & Biology Education, 2015
A letter to the Editor discussing aspects of scientific ethics that were not fully covered by the December 2014 special issue of the Journal of Microbiology & Biology Education (JMBE).
Jaime A. Teixeira da Silva
doaj   +1 more source

Special Aspects of Educational Managers’ Administrative Activity under Conditions of Distance Learning

open access: yesJournal of Curriculum and Teaching, 2022
The eruption of the COVID-19 pandemic has become a major challenge for educators around the world, forcing educational organizations to look for alternative teaching methods, namely distance learning. It forced the managers of educational organizations to carry out management activities in the conditions of remote work.
Inna Semenets-Orlova   +5 more
openaire   +2 more sources

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