Results 51 to 60 of about 409,408 (257)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

What’s Not Being Discussed, or Considered, in Science Publishing?

open access: yesJournal of Microbiology & Biology Education, 2015
A letter to the Editor discussing aspects of scientific ethics that were not fully covered by the December 2014 special issue of the Journal of Microbiology & Biology Education (JMBE).
Jaime A. Teixeira da Silva
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Égalité d’accès aux études supérieures au Canada ?

open access: yesRevue Internationale d’Éducation de Sèvres, 2004
The controls of secondary education in Canada mirror a flexible system of education which gives a special place to individual differences. Yet other constraints must be taken into account.
Marie J. Myers
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

La division du travail éducatif : deux figures de la subjectivité en tension au sein de l’institution scolaire

open access: yesQuestions Vives, 2014
Since the early 1990s, the number of new education support personnel in Quebec’s primary and secondary schools has increased considerably, complementing the teaching, administrative and professional staff (psychologists, psychoeducators, resource ...
Louis Levasseur
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The Education and Training Program Guideline for Special Guidance Teacher Competence Development in Indonesian Inclusive School

open access: yesIndonesian Journal of Disability Studies, 2018
The provision of inclusive schools in Indonesia requires the fulfillment of several aspects of Inclusive Education. The fulfillment of these needs includes curriculum, facilities and infrastructure, teachers, and learning in accordance with the ...
Ediyanto Ediyanto   +3 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

La educación en la RASD

open access: yesContextos Educativos: Revista de Educación, 2013
This paper presents a brief description of the current R.S.A.D. educational system. it focuses on kindergarten and special education. Positive aspects, as well as deficiencies and problems encountered by teachers at all levels are spelled out.
Mª Ángeles Goicoechea Gaona
doaj   +1 more source

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