Results 41 to 50 of about 2,192,804 (354)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Negative Capability? Measuring the unmeasurable in education [PDF]

open access: yes, 2016
This introductory article to the special issue of Comparative Education on measuring the unmeasurable in education considers measurement as reflecting facts and uncertainties. The notion of negative capability is used metaphorically to depict some limits
Unterhalter, ES
core   +1 more source

Geistig behinderte Kinder religiös erziehen – Herausforderungen an Pädagogik und Katechese

open access: yesThe Person and the Challenges. The Journal of Theology, Education, Canon Law and Social Studies Inspired by Pope John Paul II, 2014
Special education options are diverse and prepared to meet the needs of children with varying degrees of intellectual disabilities. However, many parents of children with an intellectual disability have a difficult time in organizing the ...
Józef Stala
doaj   +1 more source

Schools’ Perceived Readiness in Responding to Employment Policy for Person with Disability

open access: yesJKAP (Jurnal Kebijakan dan Administrasi Publik), 2021
Law Number 8 of 2016 concerning Persons with disability in Indonesia has been ratified since 2016, with one of the objectives is to expand employment opportunities for persons with disabilities.
Agustina Kustulasari   +2 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

EDUCATIONAL DEVELOPMENT PRIORITIES FOR PEOPLE WITH SPECIAL NEEDS IN UKRAINE

open access: yesEducation: Modern Discourses, 2018
The article is an attempt to outline general aspects of educational system reforming for the people with special needs in Ukraine, to disclose concisely the key ways of modernization, and to characterize positive shifts in educational area.
Viacheslav Zasenko, Lesya Prokhorenko
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Parents' choice of education for their young children: lessons for inclusive education [PDF]

open access: yes, 2006
This paper reports on aspects of a small-scale, UK-based study that investigated local discourses and practices operating for young children within a global context of commitment to inclusion.
Flewitt, Rosie, Nind, Melanie
core  

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