Results 101 to 110 of about 1,625,678 (299)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Child and Family Welfare in Sweden [PDF]

, 2002
Sweden has no special Children’s Act because regulations on children are included in the Social Services Act from 1980, supplemented by an act regulating compulsory care.
Andersson, Gunvor
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Studying the effect of the psychosocial work environment on risk of ill-health: towards a more comprehensive assessment of working conditions

Scandinavian Journal of Work, Environment & Health, 2012
The Nordic countries have a long tradition of research studying the impact of the psychosocial work environment on health (1, 2). Fittingly, the Scandinavian Journal of Work, Environment and Health has been a key place for the presentation and discussion
Reiner Rugulies
doaj   +1 more source

E-business impacts for urban freight: results from an Australian study [PDF]

, 2002
E-Business is expected to dramatically change the way business is conducted internationally, nationally, within states and at the local area level.
Ferreira, Luis, Marquez, Leorey, Smith, Nariida   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Features of assessing the professional aptitude of workers in contact with industrial vibration and noise

Медицинский вестник Юга России
A comprehensive search was conducted for literary sources devoted to the problem of assessing the professional suitability of workers in contact with industrial vibration and noise in the international database PubMed (Medline) and the scientific ...
Yu. Yu. Gorblyanskiy, E. P. Kontorovich, O. P. Ponamareva, A. V. Syachina, A. A. Bogoslovskaya   +4 more
doaj   +1 more source

Special assessment of working conditions as a mechanism for monitoring compliance with conditions labor activity

TRENDS IN THE DEVELOPMENT OF SCIENCE AND EDUCATION, 2021
A.V. Dogadkin, I.I. SHestakov, O.G. Lyubskaya   +2 more
openaire   +1 more source

Mental Health in the Workplace: Situation Analyses, Germany [PDF]

, 2000
[From Introduction] The ILO’s primary goals regarding disability are to prepare and empower people with disabilities to pursue their employment goals and facilitate access to work and job opportunities in open labour markets, while sensitising policy ...
Breucker, Gregor, International Labour Organisation, Wilken, Ulrich J.   +2 more
core   +1 more source