Results 51 to 60 of about 1,625,678 (299)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
PICES Press, Vol. 21, No. 2, Summer 2013 [PDF]
, 2013 •The 2013 Inter-sessional Science Board Meeting: A Note from the Science Board Chairman (pp. 1-4) •ICES/PICES Workshop on Global Assessment of the Implications of Climate Change on the Spatial Distribution of Fish and Fisheries (pp.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
COMPARATIVE ANALYSIS OF SPECIAL ASSESMENT OF WORKING CONDITIONS AND CERTIFICATION OF WORKPLACES
RUDN Journal of Ecology and Life Safety, 2016 А comparative analysis of special assessment of working conditions and certification of workplaces was conducted. It was revealed that the aborted procedure of certification of workplaces allows control of all production factors affecting on employers ...
G A Kulieva, M I Kochanova, D V Lunev
doaj
Training and Employment of People with Disabilities: Australia 2003 [PDF]
, 2004 [Excerpt] Training and Employment of People with Disabilities: Australia 2003 is descriptive in nature. When the ILO commissioned the researchers for the Country Study Series, each was asked to follow the comprehensive research protocol appended to this ...
O\u27Neill, Genene, Sutherland, Marie
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
ANALYSIS OF LEGISLATIVE CHANGES IN THE PROCEDURE SPECIAL ASSESSMENT OF WORKING CONDITIONS
Scientific Papers Collection of the Angarsk State Technical UniversityThe article analyzes the changes in legislation that have occurred in the procedure of special assess-ment of working ...
Oleg Varakin, Aleksandra Prusakova
openaire +1 more source
Is the Health Care System Working for Adolescents? Perspectives From Providers in Boston, Denver, Houston, and San Francisco [PDF]
, 2003 Assesses healthcare system services for adolescents in four urban areas. Includes provider perspectives on how health insurance, managed care, and other factors facilitate or impede access.
Harriette B. Fox +2 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source