Results 81 to 90 of about 1,625,678 (299)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Implications of and possible responses to climate change [PDF]

, 2009
Climate change is expected to worsen food insecurity and seriously undermines rural development prospects. It makes it harder to achieve the Millenium Development Goals and ensure a sustainable future beyond 2015.
Kahiluoto, Helena, Rötter, Reimund
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Responding to the Challenges of Violent Extremism/Terrorism Cases for United States Probation and Pretrial Services

Journal for Deradicalization, 2018
This article is intended to share the U.S. District Court of Minnesota Probation and Pretrial Services’ experiences, knowledge, practices, and processes for working with extremist/terrorist defendants and offenders with other criminal justice ...
Kevin Lowry
doaj  

Working conditions and mental health of migrants and refugees in Europe considering cultural origin– a systematic review

BMC Public Health
Background Migrants and refugees/asylum seekers, as a large part of the European work force, are often confronted with unfavorable working conditions in the host country.
Regina Herold, Marietta Lieb, Andrea Borho, Amanda Voss, Susanne Unverzagt, Eva Morawa, Eva Rothermund, Yesim Erim   +7 more
doaj   +1 more source

The Analysis of Economic Activity of the Perm Industrial Complex in the 1920s of the 20th Century

Учёт. Анализ. Аудит, 2019
The correct assessment of the current level of development of the analysis of financial and economic activities of enterprises and the influence of its theory and science on analytical practice largely depends on the knowledge of the history of its ...
V. V. Shcherbatyuk
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Children's Databases - Safety and Privacy [PDF]

, 2006
This report describes in detail the policy background, the systems that are being built, the problems with them, and the legal situation in the UK. An appendix looks at Europe, and examines in particular detail how France and Germany have dealt with ...
Anderson, R, Brown, I, Clayton, R, Dowty, T, Korff, D, Munro, E   +5 more
core  

Lawyer Speech in the Regulatory State [PDF]

, 2016
A lawyer’s speech as advisor and advocate not only holds First Amendment value for the client and for the public, but also for the functioning of American democracy.
Knake, Renee Newman
core   +2 more sources