Results 51 to 60 of about 6,925,264 (262)

A Survey on the Contents of Khosro Nama [PDF]

open access: yesمجله مطالعات ایرانی, 2019
. Introduction    Khosro Nama is one of the outstanding lyrical works in Persian literature. This poem portrays the romance of Gol o Hormuz and the related events.
sara gerami, Zarrintaj Varedi
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Jeffrey Koperski, DIVINE ACTION, DETERMINISM, AND LAWS OF NATURE [Book review]

open access: yes, 2023
Jeffrey Koperski offers a philosopher of science’s intervention in the debate over divine action, with the dual purpose of providing a scientifically-historically informed clarification of key concepts such as “determinism” and “law of nature,” as well ...
Daniel Rubio (17410200)
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

LEVELS OF ANALYSIS IN PHILOSOPHY, RELIGION, AND SCIENCE

open access: yesZygon, 2015
This article introduces a model of levels of analysis applied to statements found in philosophical, scientific, and religious discourses in order to facilitate a more accurate description of the relation between science and religion.
doaj   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

THE UNIFORMITY OF NATURAL LAWS IN VICTORIAN BRITAIN: NATURALISM, THEISM, AND SCIENTIFIC PRACTICE

open access: yesZygon, 2011
.  A historical perspective allows for a different view on the compatibility of theistic views with a crucial foundation of modern scientific practice: the uniformity of nature, which states that the laws of nature are unbroken through time and space ...
doaj   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

SHOULD A CHRISTIAN ADOPT METHODOLOGICAL NATURALISM?

open access: yesZygon, 2017
It has become standard practice for scientists to avoid the possibility of references to God by adopting methodological naturalism (MN), a method that assumes that the reality of the universe, as it can be accessed by empirical enquiry, is to be ...
doaj   +2 more sources

Escola de Bethlem: amor e pedagogia [PDF]

open access: yesVia Spiritus, 2010
Escola de Bethlem [School of Bethlem], a work published in Évora in 1678, is a result of two factors: in the first place, the author’s concern (the Jesuit priest Alexandre de Gusmão (1629-1724), that founded the Bethlehem Seminar in the State of Bahia ...
Sara Augusto
doaj  

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