Results 51 to 60 of about 862 (216)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

God, time and eternity: philosophical foundations for a defence of divine timelessness [PDF]

open access: yes, 2007
The past two decades have seen an almost exponential growth in publications on the topic of divine eternity and the general area of 'God and time'. Increasing appeal is made to arguments and resources which ranges widely through contemporary science and ...
Foyle, Stuart Mark
core  

Special Divine Insight: Escaping the Snow Queen's Palace [PDF]

open access: yes, 2015
Insights play a role in every field that can be called knowledge, but are of particular interest to the philosophy of religion and special divine action.
Andrew Pinsent   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Providence

open access: yesSt Andrews Encyclopaedia of Theology, 2022
Though not linguistically prominent in Christian scripture, the theology of providence captures several recurring scriptural themes. These include the order of the cosmos, the wisdom reflected in the natural and social worlds, the direction of the ...
David Fergusson
doaj  

The Educational Approach of Sharh at-Ta'arrof to the Story of Prophet Adam (PBUH) in the Qur'an [PDF]

open access: yesLiterary Arts, 2019
Sharh at-Ta'arrof is a very extensive and elaborate work on Kalaabaadi's At-Ta'arrof written in Persian and is in fact the oldest Sufi text of Persian language.
Behjat Forughi Moghaddam, Taghi Eje’ee
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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