Results 81 to 90 of about 6,925,264 (262)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Comparative Study of the principle of Penal and Criminal Laws in Islam and Judaism [PDF]

open access: yesComparative Theology, 2013
In the field of religious studies, study of previous religions and orders is important, because divine religions have a one truth and essence; Judaism, Christianity and Islam are relative religions and have a common history.
Mohammad Reza Haji Esmaili   +1 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Divine Agency and Divine Action, Volume I

open access: yes, 2017
This book lays the groundwork for a constructive contribution to the contemporary debate regarding divine action. It argues that the concept of divine action is not a closed concept, like knowledge, but an open concept with a variety of context-dependent
William J. Abraham
core   +1 more source

How God Acts

open access: yes, 2010
How does the Christian doctrine of creation square with the picture of an evolving universe we receive from science today? How do the badly predatory behavior and wasteful extinction of whole species fit in with a Christian understanding? These and a host of related questions raised by ordinary experience are tackled in this important and original work
openaire   +2 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Divine Agency and Divine Action

open access: yes, 2017
The fundamental problems that have arisen over the last half-century in treatments of divine action in the Christian tradition stem from a failure to come to terms with the concept of action.
William J. Abraham
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Divine Agency and Divine Action, Volume II

open access: yes, 2017
This book builds upon the groundwork laid in the first volume, where it was established that no generic concept of action will suffice for understanding the character of divine actions explicit in the Christian faith.
William J. Abraham
core   +1 more source

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