Results 101 to 110 of about 11,214,713 (348)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Special Education as Spiritual Warfare

open access: yes, 2006
This article reflects on a theology of exceptionalities and the hermeneutics of special education, and develops the notion that there is an aspect of special education which can be understood as spiritual warfare. The main thesis is that providing access
Anderson, David
core  

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Support for the beginning special educator through high quality mentoring [PDF]

open access: yes, 2012
Approximately 50% of school districts across the nation have reported barriers in obtaining highly qualified teachers (U.S. Department of Education, 2009). Beginning special education teachers report that they often feel they lack the prerequisite skills
Madigan, Jennifer C, Scroth-Cavataio, G
core   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

An exploratory study of children’s expressive language productivity in relation to teachers’ use of communication-supporting strategies

open access: yesFrontiers in Education
Supporting children’s language development, particularly oral language, is crucial as it constitutes the basis for the further development of literacy skills. This study explored patterns of primary school children’s expressive language productivity over
Karin Edlund   +3 more
doaj   +1 more source

A systematic review of pedagogical approaches that can effectively include children with special educational needs in mainstream classrooms with a particular focus on peer group interactive approaches [PDF]

open access: yes, 2004
The broad background to this review is a long history of concepts of special pupils and special education, and a faith in special pedagogical approaches. The rise of inclusive schools and some important critiques of special pedagogy (e.g.
Collins, J.   +5 more
core  

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Music therapy as social skill intervention for children with comorbid ASD and ID: study protocol for a randomized controlled trial

open access: yesBMC Pediatrics, 2020
Background Autism spectrum disorder (ASD) is a developmental impairment characterized by persistent deficits in social communication and interactions, and over half of children with ASD possess below average intellectual ability (IQ 
Yen Na Yum   +3 more
doaj   +1 more source

From library skills to information literacy [PDF]

open access: yes, 2005
The application of new technologies and the acquisition of new sources and methods of information dissemination, as well as the provision of libraries services, requires the special education of the users in order to take advantage of these sources and ...
Nikitakis, Michail   +2 more
core  

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