Results 91 to 100 of about 3,476,529 (285)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Public Funding for Art: Chicago Compared with 12 Peer Regions [PDF]

, 2014
Supported in part by Arts Alliance Illinois, and with the cooperation of several local arts agencies, including Chicago's Department of Cultural Affairs and Special events, and of the National Assembly of State Arts Agencies.This study compares the ...
Jennifer Novak-Leonard, Patience E. Baach   +1 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Prediction of Large Events on a Dynamical Model of a Fault

, 1993
We present results for long term and intermediate term prediction algorithms applied to a simple mechanical model of a fault. We use long term prediction methods based, for example, on the distribution of repeat times between large events to establish a ...
Aki, Archuletta, B. E. Shaw, Bak, Bakun, Bakun, Burridge, Carlson, Carlson, Carlson, Carlson, Chen, Davis, Davison, Dieterich, Gabrielov, Healy, J. M. Carlson, Kanamori, Keilis-Borok, Keilis-Borok, Keilis-Borok, Kiremidjian, Langer, Langer, Malin, McNalley, Mogi, Molchan, Molchan, Nishenko, Pacheco, S. L. Pepke, Scholz, Schwartz, Shaw, Shaw, Shaw, Shimazaki, Sykes, Thatcher, Vasconcelos, Ward, Wesnousky, Working Group on California Earthquake Prediction, Working Group on California Earthquake Prediction (WG-CEP), Wyss   +46 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Number- and size-controlled rainfall regimes in the Netherlands: physical reality or statistical mirage? [PDF]

Atmospheric Measurement Techniques
An experimental study aimed at identifying special rainfall regimes with the help of co-located disdrometers is performed. Eight potentially special events (i.e., four number-controlled events and four size-controlled events) are identified and examined.
M. Schleiss
doaj   +1 more source

Party Conventions Are a Free-For-All for Influence Peddling: The Soft Money Loophole for Lobbyists [PDF]

, 2008
The Democratic and Republican national conventions are supposed to be publicly financed electoral events with reasonable ethics restrictions on influence-peddling by lobbyists. However, the conventions have become mostly privately financed soirees funded
Angela Canterbury, Craig Holman, Zoe Bridges-Curry   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Festival Spaces and the Visitor Experience [PDF]

, 2007
A festival implies a special use of space for both the organiser and the visitor. On the practical level of events management, it is a series of temporary per - formance venues presenting special organisational problems. For the festivalgoers, it is a
Morgan, Michael
core