Results 91 to 100 of about 5,042,936 (304)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Ingarden mechanical systems with special external forces
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 In the present paper we study a remarcable particular case of Finslerian mechanical system, called Ingarden mechanical system. This is defined by a 4-uple ∑IFⁿ = (M, F2, N, Fe) where M is the configuration space, Fn = (M, F, (x, y)) = (M, α, (x, y) + β ...
Lungu Otilia, Nimineţ Valer
doaj +1 more source
, 1943 Hoyle, J. Annotated bibliography of Australian domestic cookery books, 1860s to 1950, 57; Electronic reproduction. Canberra, A.C.T.
Allied Forces. South West Pacific Area.
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Armored Force Command and Center. Army Ground Forces study no. 27.
, 2020 The history presented in this study is written from the point of view of officers who were directly responsible for the development of armor in the U.S. Army in World War II.
Historical Section, Army Ground Forces
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
LifeContusions are highly prevalent injuries in the armed forces. They can substantially impair physical performance, particularly in special operations forces, where operational readiness depends on maintaining a high level of physical fitness ...
Ignacio Aparicio-Arranz +5 more
doaj +1 more source
Market Forces superannuation survey: 2016
, 2016 This was an online survey. The survey was in the field from Monday 15th August to Friday 19th August 2016. The survey fieldwork was conducted by the Online Research Unit (ORU). Data tables were prepared by Essential Research.
Market Forces
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
History of the activation of headquarters of the Fifteenth Army. Army Ground Forces study no. 19.
, 2020 This is an account of the activation of Headquarters of the Fifteenth Army, and a narration of the activities prior to overseas shipment. The actual history began after the Fifteenth Army arrived overseas, and is not covered in this short study.
Historical Section, Army Ground Forces
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