Results 101 to 110 of about 3,569,062 (330)

Stress–Strength Reliability of the Type P(X < Y) for Birnbaum–Saunders Components: A General Result, Simulations and Real Data Set Applications

open access: yesModelling
An exact expression for R=P ...
Felipe S. Quintino   +3 more
doaj   +1 more source

Umbral calculus and special functions

open access: yesAdvances in Mathematics, 1988
Let P denote the commutative algebra of all polynomials in a single variable x with coefficients in a field K (real or complex) of characteristic zero. Let P * be the vector space of all linear functionals on P and the action of a linear functional L on a polynomial P(x) is denoted by \(\).
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Fourier Series Related to p-Trigonometric Functions

open access: yesAxioms
In this paper, we introduce the concept of generalized Fourier series, generated by the p-trigonometric functions, namely cosp and sinp, recently introduced related to the generalized complex numbers systems.
Ali Hamzah Alibrahim, Saptarshi Das
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Software needs in special functions

open access: yesJournal of Computational and Applied Mathematics, 1996
This paper scrutinizes numerical algorithms for computing special functions and identifies these functions for which software is lacking, in particular, in cases where algorithms have been described in journal articles. The author gives cumulative scores over 44 functions instoled in intermediate libraries, comprehensive libraries and interactive ...
openaire   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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