Results 111 to 120 of about 3,569,062 (330)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Eigenfunction Expansions of Functions Describing Systems with Symmetries
Symmetry, Integrability and Geometry: Methods and Applications, 2007 Physical systems with symmetries are described by functions containing kinematical and dynamical parts. We consider the case when kinematical symmetries are described by a noncompact semisimple real Lie group $G$.
Ivan Kachuryk, Anatoliy Klimyk
doaj
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
OBSERVATIONS ON THE FUNCTIONS OF THE COLON, WITH SPECIAL REFERENCE TO THE MOVEMENTS OF ENEMATA [PDF]
, 1914 Hugh Drummond
openalex +1 more source
On a special class of abelian functions [PDF]
Bulletin of the American Mathematical Society, 1945 Not ...
openaire +3 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012 Two special functions, concerning Mittag–Leffler type functions, are considered. The first is the modification of generalized Mittag–Leffler type function, introduced by A. A. Kilbas and M. Saigo; the second is the special case of the first one.
Eugeniy N Ogorodnikov
doaj
Analytical Approximations as Close as Desired to Special Functions
AxiomsWe introduce a modern methodology for constructing global analytical approximations of special functions over their entire domains. By integrating the traditional method of matching asymptotic expansions—enhanced with Padé approximants—with differential ...
Aviv Orly
doaj +1 more source
Anatomy of the Brain and Spinal Cord, with Special Reference to Mechanism and Function. [PDF]
, 1908 openalex +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source