Results 131 to 140 of about 3,569,062 (330)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A Recurrence Relation Approach to Higher Order Quantum Superintegrability

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2011
We develop our method to prove quantum superintegrability of an integrable 2D system, based on recurrence relations obeyed by the eigenfunctions of the system with respect to separable coordinates.
Ernie G. Kalnins   +2 more
doaj   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Chebyshev polynomials of the first kind and the univariate Lommel function: Integral representations

open access: yesOpen Mathematics
This study investigates a number of integrals possessing products of different indices of the univariate Lommel function, sμ,ν(a){s}_{\mu ,\nu }\left(a), with various elementary and special functions.
da Fonseca Carlos M.   +2 more
doaj   +1 more source

Functional inequalities involving special functions

open access: yesJournal of Mathematical Analysis and Applications, 2006
AbstractLet up(x) be the generalized and normalized Bessel function depending on parameters b,c,p and let σ(r)=up(1−r2)/up(r2), r∈(0,1). Motivated by an open problem of Anderson, Vamanamurthy, and Vuorinen we prove that σ(r1)σ(r2)⩽σ(r1r2) for all r1,r2∈(0,1) for certain conditions on the parameters b,c,p.
openaire   +1 more source

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