Results 51 to 60 of about 16,340,595 (288)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Special Interest Group [PDF]

open access: yesPsychiatric Bulletin, 1993
In June 1987 Council approved the establishment of Special Interest Groups.
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Embedded Legendre expansion layer of physics-informed neural network with restarting strategy in solving partial differential equation in fluid dynamics

open access: yesResults in Engineering
Partial differential equations (PDEs) have long been used to describe and solve problems in fluid dynamics. The advent of Artificial Neural Networks (ANNs) has revolutionized the ways of tackling many problems, including the landscape of scientific ...
Danang A. Pratama   +3 more
doaj   +1 more source

Maximal Injective Real W∗-Subalgebras of Tensor Products of Real W∗-Algebras

open access: yesAbstract and Applied Analysis, 2022
It is known that injective (complex or real) W∗-algebras with particular factors have been studied well enough. In the arbitrary cases, i.e., in noninjective case, to investigate (up to isomorphism) W∗-algebras is hard enough, in particular, there exist ...
A. A. Rakhimov   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Mass media and special interest groups [PDF]

open access: yesJournal of Economic Behavior & Organization, 2011
Media revenues are an important determinant of media behavior. It is generally accepted that news coverage depends not only on the preferences of media consumers but also on the preferences of advertisers or subsidizing groups. However, existing models reach the opposite conclusions about the relationship between the profitability of advertising and ...
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Circular Intuitionistic Fuzzy Dombi Aggregation Operators and Their Application to Marine Fuel Selection

open access: yesIEEE Access
Higher-order fuzzy sets have emerged as effective tools for decision-making under uncertainty. Among these, the circular intuitionistic fuzzy set (CIFS) has recently been introduced to better represent uncertain information.
Nuraini Rahim   +3 more
doaj   +1 more source

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