Results 61 to 70 of about 7,090,459 (295)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Jackie Dooley & Stephen MacLeod & Pauline Manaka

open access: yes, 2016
Oral history with Jackie Dooley ’73, former UCI Libraries Head of Special Collections & Archives, Stephen MacLeod, Public Services Librarian, Special Collections & Archives, and Pauline Manaka, Research Librarian for Anthropology, Demographic and Social ...
UCI Libraries. Department of Special Collections
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The Development of Socially Inclusive Libraries in Šiauliai Region Providing Services for Children and Youth with Special Needs

open access: yesJaunųjų Mokslininkų Darbai, 2020
One of socially vulnerable groups in society, which often faces social exclusion problems, is children and youth with special needs. In Lithuania, children with special needs comprise about 12.5 percent from the total number of children and youth up
Kristina Kulikauskienė
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

UW History Wall by UW Libraries Special Collections

open access: yes, 1891
Collage/multi-genre display5’ x 24’4”ExcellentThe University of Washington History Wall is a selection of images and artifacts drawn from each decade beginning with the founding of the University until the early 1990s. The items shown here represent only
UW Libraries Special Collections
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Contemporary librarianship and special collections issues: a case study in manuscript collections of Timbuktu and other Malian cities

open access: yesJLIS.it, 2017
The article addresses the issues and challenges of special collections management through the case study of Timbuktu manuscript collections. The dual issues of preservation and access are presented in the light of current librarianship trends ...
Maria Luisa Russo
doaj   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Vendor partnerships with engineering libraries partnering with Knovel : case studies in information outreach [PDF]

open access: yes, 2005
The engineering library plays a critical role in initiating and maintaining the conduit between vendors of engineering information and the users of that information—faculty, students, and researchers.
Van Epps, Amy S.   +4 more
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Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

United States and Canada, map librarians, 1954

open access: yes, 1954
Inset: Alaska -- Hawaii -- [Eastern Seaboard].; "Data from Map Collections in the United States and Canada: a Directory; Special Libraries Association, 1954."; made by Patricia Ann Greechie Alonso, based on the Directory of Map Librarians and Collections,
Alonso, P.;
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