Results 61 to 70 of about 964 (201)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Hyperconvex hulls in catergories of quasi-metric spaces [PDF]
, 2014 Includes bibliographical references.Isbell showed that every metric space has an injective hull, that is, every metric space has a “minimal” hyperconvex metric superspace. Dress then showed that the hyperconvex hull is a tight extension.
Agyingi, Collins Amburo
core
Metric Based Upscaling for Partial Differential Equations with a Continuum of Scales [PDF]
, 2007 Numerical upscaling of problems with multiple scale structures have attracted increasing attention in recent years. In particular, problems with non-separable scales pose a great challenge to mathematical analysis and simulation.
Zhang, Lei
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Indexing and Retrieval of 3D Articulated Geometry Models [PDF]
, 2009 In this PhD research study, we focus on building a content-based search engine for 3D articulated geometry models. 3D models are essential components in nowadays graphic applications, and are widely used in the game, animation and movies production ...
TAM, KWOK,LEUNG, Tam, Kwok Leung
core
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
The fuzzy metric spaces and the fixed point theorems [PDF]
, 2004 Yüksek LisansÖZET Beş bölümden oluşan bu çalışmada, değişik türden fonksiyonlar sınıfı için, fuzzy metrik uzaylarda daha önce çalışılmış olan sabit nokta teoremleri incelenmiş ve onların bazı genellemeleri yapılmış ve klasik metrik uzaylara has özel ...
Gündoğdu, Funda
core
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Visualising the structure of document search results: A comparison of graph theoretic approaches [PDF]
, 2010 This is the post-print of the article - Copyright @ 2010 Sage PublicationsPrevious work has shown that distance-similarity visualisation or ‘spatialisation’ can provide a potentially useful context in which to browse the results of a query search ...
Cribbin, T
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source