Results 61 to 70 of about 800,165 (296)

Development and application of “Special defibrillator for teaching and training”

open access: yesEuropean Journal of Medical Research, 2022
Background To provide an economical and practical defibrillator for first aid teaching and training, to reduce the cost of teaching and training, increase teaching and training equipment, provide trainees with more hands-on training sessions, and improve
Liping Xing   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

THE STATE OF DEVELOPMENT AND RELATIONS OF COORDINATION ABILITIES OF PRIMARY SCHOOL PUPILS WHO BELONG TO SPECIAL MEDICAL GROUP

open access: yesJournal of Education, Health and Sport, 2015
Kushnir Yana. The state of development and relations of coordination abilities of primary school pupils who belong to special medical group. Journal of Education, Health and Sport. 2015;5(11):441-452. ISSN 2391-8306.
Yana Kushnir
doaj  

Innovative health saving technologies in classes of special medical group

open access: yesKANT, 2020
At the stage of nowdays the main part of physical education system for special medical groups updates and creates intergative innovative methods of selection and aprobation of modern academic activity. The object of our research was gain in quality improvement of the academic activity of physical education for special medical groups.
Natalia Golyakova   +2 more
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Content of the physical education method for the students of special medical group

open access: yesUchenye zapiski universiteta imeni P.F. Lesgafta, 2014
Аннотация В статье представлена технология физического воспитания студенток, имеющих отклонения в состоянии дыхательной системы. Содержательная часть технологии представлена тремя блоками: контрольным, экспертным и блоком управляющих воздействий. Особенностью представленной технологии является использование адаптированных средств оздоровительной ...
Larisa Patrusheva, Elena Tokar
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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