Results 101 to 110 of about 668,739 (287)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Exercise students of special medical groups such as disease prevention [PDF]
, 2015 Іваночко О. Фізичні навантаження студенток спеціальних медичних груп, як профілактика захворювань / О. Іваночко, Н. Киван-Мультан, О.. Чичкан // Науковий часопис Національного педагогічного університету імені М. П. Драгоманова.
Киван-Мультан, Н. +5 more
core
Physical Education of Students, 2013 The method of application of physical drills of hatha-yoga is presented on educational trainings on physical culture with students. The volume of empiric information made more than 10000 measurings.
A.A. Gorelov +2 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Model of Adaptive Physical Education for Students of Special Medical Groups
, 2020 In this article the actual questions arising at the organization and carrying out of discipline of physical education of students of special medical groups in higher education institutions are considered. The authors, based on many years of experience in
Дюсенов, О. +1 more
core
Physical Education Theory and Methodology, 2017 The objective is the dynamics of psychophysiological functions of students of special medical group with cardiovascular diseases under the influence of the experimental control technique in their physical education is carry through analyze. Materials &
В. М. Корягин +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Evaluation of the teeth and jaw deformities in children with special health needs
, 2019 Introduction: Special needs children (SNC) are a public health concern and need specific oral care. Globally, SNC have a significantly higher prevalence of teeth and jaw deformities (TJD).
Andreeva, Radosveta; Medical University of Varna
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source