Results 81 to 90 of about 2,191,257 (298)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The state ob the college students health [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The paper focuses on the problem of health worsening among people suffering from many different diseases. Young people make up risk group. The article highlights the health conditions of pedagogical and medical college students.
Vovchenko I.I., Tunik N. Ts., Stadnik T.V.   +2 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The role of nutrition in maintaining health and physical activity among adolescents assigned to special medical groups

International Journal of Adolescent Medicine and Health
This study aimed to assess the dietary patterns of adolescents to develop targeted medical and organizational interventions for optimizing nutrition and physical activity.
Doszhanova Gulnur, Abduldayeva Aigul, Iskakova Saule, Ibrayeva Danara, Kuanyshbayeva Gaukhar   +4 more
doaj   +1 more source

Рабочая программа учебной дисциплины "Лечебная физическая культура в специальных медицинских группах" [PDF]

, 2017
The program for academic course "Remedial physical culture in special medical groups" is designed for students of training areas: 6.010201 - Physical education, field of study: 0102 - Physical education, sport and healthРобоча програма навчальної ...
Бісмак, Олена Василівна
core  

DYNAMIC CONTROL OF LOAD IN SPECIAL MEDICAL GROUP STUDENTS DURING PE ACTIVITIES

Human Sport Medicine, 2020
Aim. The article aims to evaluate the effectiveness of dynamic control of the workload during PE activities in special medical group students (SMG) using heart rate (HR) monitors. Materials and methods. The research involved 30 students with chronic pathology of the organs of vision, respiratory, cardiovascular, musculoskeletal, nervous and ...
E Ketlerova, L Kodaneva
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Boundaries in school: Educational settings for pupils perceived as different

Scandinavian Journal of Disability Research, 2009
This paper analyses the contradictions in the Swedish school organisation between the intentions of an implemented integration of pupils with disabilities, and the actual dramatic increase of pupils enrolled in special units. The study is a multiple case
Mara Westling Allodi, Siv Fischbein
doaj   +1 more source

Differences between physicians in the likelihood of referral and acceptance of elderly patients for dialysis-influence of age and comorbidity [PDF]

, 2007
BACKGROUND: Incidence of dialysis in elderly patients in the Netherlands is low compared to other countries. This study aims to assess the impact of patients' age and comorbidity on the likelihood of referral and acceptance of patients for dialysis and ...
De Jong, P.E., Dijkstra, G.J., Gansevoort, R.T., Huisman, R.M., Reijneveld, S.A., Visser, A.   +5 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source