Results 101 to 110 of about 2,919,146 (356)
Quantum gauge freedom in very special relativity
Nuclear Physics B, 2017 We demonstrate Yokoyama gaugeon formalism for the Abelian one-form gauge (Maxwell) as well as for Abelian two-form gauge theory in the very special relativity (VSR) framework.
Sudhaker Upadhyay, Prasanta K. Panigrahi
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Peer instruction to address alternative conceptions in Einstein's special relativity
Revista Brasileira de Ensino de FísicaIn education, decades have been spent investigating what kind of beliefs and attitudes students may have in relation to learning. The relevance of these lies on the implications that it brings concerning students' alternative conceptions.
Manuel S. Alvarez-Alvarado +2 more
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Down to earth relativity [PDF]
, 1978 The basic concepts of the special and general theories of relativity are described. Simple examples are given to illustrate the effect of relativity on measurements of time and frequency in the near-earth ...
Shapiro, I. I.
core +1 more source
Gravitation and Special Relativity [PDF]
Journal of Dynamics and Differential Equations, 2013 29 pages, 1 ...
openaire +4 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Axion mass bound in very special relativity
Physics Letters B, 2017 In this paper we propose a very special relativity (VSR)-inspired description of the axion electrodynamics. This proposal is based upon the construction of a proper study of the SIM(2)–VSR gauge-symmetry.
R. Bufalo, S. Upadhyay
doaj +1 more source