Results 151 to 160 of about 3,787,339 (300)

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Special relativity : a heuristic approach /

open access: yes
Includes bibliographical references and index.Online resource; title from PDF title page (ScienceDirect, viewed May 19, 2017).Front Cover; Special Relativity; Copyright; Contents; Preface; List of Symbols, Phrases, and Acronyms; Note to the Reader; 1 ...
Hassani, Sadri,author.
core  

Presentism in a World Denied Instantaneous Signals [PDF]

open access: yes, 2011
The special theory of relativity (STR) is widely regarded as the primary threat to the otherwise intuitive presentist worldview. In particular, both the relativity and conventionality of simultaneity within STR appear to undermine presentism and support
Nasmith, Benjamin B
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Special Theory of Relativity and the Lorentz Force [PDF]

open access: yes, 2003
Efforts to demonstrate that the application of Lorentz transformations leads to the form Y' = [Y - (v/c)N] (at least to the leading orders of approximation), which has been elevated to the criterion for the validity of STR , has been the main point in ...
Noninski, Vesselin
core  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Special Relativity, Coexistence and Temporal Parts: A Reply to Gilmore [PDF]

open access: yes, 2004
In two earlier works (Balashov, 2000a and 2000b), I have argued that considerations based on special relativity and the notion of coexistence favor the perdurance view of persistence over its endurance rival. Cody Gilmore (2002) has subjected my argument
Balashov, Yuri
core  

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