Results 61 to 70 of about 8,859 (258)

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Special Theory of Relativity without special assumptions and tachyonic motion

open access: yesCondensed Matter Physics, 2010
The most general form of transformations of space-time coordinates in Special Theory of Relativity based solely on physical assumptions is described. Only the linearity of space-time transformations and the constancy of the speed of light are used as ...
E. Kapuścik
doaj   +1 more source

Unruh effect of nonlocal field theories with a minimal length

open access: yesPhysics Letters B, 2018
The nonlocal field theory commonly requires a minimal length, and so it appears to formulate the nonlocal theory in terms of the doubly special relativity which makes the speed of light and the minimal length invariant simultaneously. We set up a generic
Yongwan Gim, Hwajin Um, Wontae Kim
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The kinetic relativity theory – hiding in plain sight

open access: yesOpen Physics
A question in physics is whether Special Relativity (SR) is the only theory that explains relativistic behavior. SR measures time dilation by a relative velocity between two frames.
Loen Mark V.
doaj   +1 more source

Infrared Regularization of Very Special Relativity Models

open access: yesUniverse
We extend the Sim(2) invariant infrared regularization of Very Special Relativity models, that we have proposed recently, to include γ5 Dirac matrix. Then, we solve the Very Special Relativity Schwinger model, find the chiral anomaly, and clarify its ...
Jorge Alfaro
doaj   +1 more source

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