Results 71 to 80 of about 4,127,357 (252)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Tense, Perspectival Properties, and Special Relativity

open access: yesManuscrito
Tensism is the view that tense is not merely a property of language and the mind (narrowly individuated), but of the world itself. Perspectivalism extends this idea to all perspectival properties be they person (e.g. first person vs.
Peter Ludlow
doaj   +1 more source

Schwinger model à la Very Special Relativity

open access: yesPhysics Letters B, 2019
In this work, we show that Lorentz invariant theories in 1+1 dimensions admit new terms inspired by Very Special Relativity (VSR) theories. We have studied the Schwinger model in VSR.
Jorge Alfaro, Alex Soto
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Alternative conventions and geometry for special relativity [PDF]

open access: yes, 2004
This paper argues that Einstein’s conventionalist definition of time is sufficient for, but not necessary to the geometric modelling of Special Relativity.
Crabbe, A
core  

A Glimpse of Special Theory of Relativity [PDF]

open access: yes, 2017
This article provides a brief outline of Special Theory of Relativity. The physics before the relativity, the special relativity in itself, and the consequences of special relativity are discussed ...
Dahal, Arjun
core   +3 more sources

Peer instruction to address alternative conceptions in Einstein's special relativity

open access: yesRevista Brasileira de Ensino de Física
In education, decades have been spent investigating what kind of beliefs and attitudes students may have in relation to learning. The relevance of these lies on the implications that it brings concerning students' alternative conceptions.
Manuel S. Alvarez-Alvarado   +2 more
doaj   +1 more source

Quantum gauge freedom in very special relativity

open access: yesNuclear Physics B, 2017
We demonstrate Yokoyama gaugeon formalism for the Abelian one-form gauge (Maxwell) as well as for Abelian two-form gauge theory in the very special relativity (VSR) framework.
Sudhaker Upadhyay, Prasanta K. Panigrahi
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Space-time, relativity and quantum mechanics: In search of a deeper connection [PDF]

open access: yes, 2013
It has been shown that the Lorentz transformations in special relativity can be derived in terms of the principle of relativity and certain properties of space and time such as homogeneity.
Gao, Shan, Shan Gao
core  

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