Results 71 to 80 of about 2,919,146 (356)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Relativistic kinematics beyond Special Relativity

open access: yes, 2012
In the context of departures from Special Relativity written as a momentum power expansion in the inverse of an ultraviolet energy scale M, we derive the constraints that the relativity principle imposes between coefficients of a deformed composition law,
D. Mattingly   +3 more
core   +1 more source

Non-Abelian fields in very special relativity [PDF]

open access: yes, 2013
We study non-Abelian fields in the context of very special relativity (VSR). For this we define the covariant derivative and the gauge field gauge transformations, both of them involving a fixed null vector $n_{\mu}$, related to the VSR breaking of the ...
J. Alfaro, V. Rivelles
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Retardation in Special Relativity and the Design of a Relativistic Motor

open access: yes, 2017
The Newton third law states that any action is countered by a reaction of equal magnitude but opposite direction. The total force in a system not affected by external forces is thus zero.
A. Yahalom
semanticscholar   +1 more source

Doubly special relativity from quantum cellular automata [PDF]

open access: yes, 2013
It is shown how a doubly special relativity model can emerge from a quantum cellular automaton description of the evolution of countably many interacting quantum systems.
Alexandre Bibeau-Delisle   +4 more
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Design, analysis and reformulation of a didactic sequence for teaching the special theory of relativity in high school

open access: yesRevista Brasileira de Ensino de Física
In this work, we design, implement and analyze a didactic sequence for the teaching of the basic topics of special relativity theory in high school. The sequence proposes a series of situations, specially designed to allow the emergence of the central ...
María Rita Otero   +2 more
doaj   +1 more source

The Function of the Second Postulate in Special Relativity [PDF]

open access: yes, 2016
Many authors noted that the principle of relativity, together with space-time symmetries, suffices to derive Lorentz-like coordinate transformations between inertial frames.
Drory, Alon
core  

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