Results 211 to 220 of about 291,167 (258)

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Caring in Context: Development of a Family-Centred and Cross-Sectoral Framework to Support Young Carers. [PDF]

Healthcare (Basel)
Frech M, Nagl-Cupal M, Kaiser S, Spittel AM.   +3 more
europepmc   +1 more source

Challenges and needs among pediatric oncology providers in caring for pediatric brain tumor patients and survivors: A qualitative study. [PDF]

Int J Clin Health Psychol
Lefebvre C, Gazzo G, Defachelles AS, El Hakim C, Mezloy-Destracque M, Desjardins L, Entz-Werlé N, Raimbault S, Gehin W, Lamore K.   +9 more
europepmc   +1 more source

Time to act: climate change and its impacts on women's sexual and reproductive health. [PDF]

Rev Bras Ginecol Obstet
Surita FG, Sánchez ODR, da Mata JAL.
europepmc   +1 more source

Management of Chronic Health Situations. [PDF]

Healthcare (Basel)
Sousa L, Käppler C, Faleiros F, Alburquerque G, José H.   +4 more
europepmc   +1 more source

Russian full-scale invasion of Ukraine: epidemiological challenges for public health. [PDF]

BMJ Glob Health
Chumachenko D, Chumachenko T.
europepmc   +1 more source